DPG — A Link between Blood Acid-Base Status and Respiratory Function

  • Jerry H. Meldon
  • Omar K. Abboud
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 159)


The intimate connection between the acid-base status and respiratory function of blood is a fundamental concept of physiology. Recognition of this fact effectively dates back to the report by Bohr et al. (1904) of the effect of CO2 on the oxyhemglobin dissociation curve (ODC), since it later became clear that CO2-mediated pH changes are primarily responsible for the “Bohr effect”.


Respiratory Function Oxygen Transport Intimate Connection Bohr Effect Allosteric Binding 
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Copyright information

© Plenum Press, New York 1983

Authors and Affiliations

  • Jerry H. Meldon
    • 1
  • Omar K. Abboud
    • 1
  1. 1.Chemical Engineering DepartmentTufts UniversityMedfordUSA

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