Cerebrovascular Responses to Oxygen During Barbiturate Anesthesia
In a previous study we reported that increases in local cerebral blood flow (1CBF) during progressive reduction of PaO2 from 300 to 40 torr was casually related to an increase in cortical hydrogen ion concentration (H+)t (Shinozuka and Nemota, this Symposium). Brain tissue PO2 (PtO2) was also linearly related to (H+)t suggesting that a fall in PtO2 caused an increase in (H+)t which affected 1CBF.
KeywordsParietal Cortex Pyridine Nucleotide Pentobarbital Anesthesia Local Cerebral Blood Flow Hydrogen Clearance
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