Risk Factors for Atherosclerosis

  • Henry C. McGillJr.
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 104)


Nearly three decades of intensive epidemiological investigation have identified a group of characteristics that predict an individual’s probability of developing clinically manifest disease due to atherosclerosis -- myocardial infarction, sudden death, angina pectoris, stroke, or peripheral vascular disease. These characteristics are known as “risk factors,” a descriptive but noncommittal term which avoids the question of whether these characteristics are causative agents, intervening variables, early manifestations of disease, or secondary indicators of an underlying disturbance.


Coronary Heart Disease Serum Cholesterol Atherosclerotic Disease Artery Wall Fatty Streak 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. 1.
    McGill, H.C., Jr. (1968) The Geographic Pathology of Atherosclerosis, Williams & Wilkins, Baltimore, 193 pp.Google Scholar
  2. 2.
    Bierman, E.L., and Ross, R. (1977) in Atherosclerosis Reviews, Vol. 2, (Gotto, A.M. and Paoletti, R., Eds.), Raven Press, New York, pp. 79–111.Google Scholar
  3. 3.
    McGill, H.C., Jr., and Stern, M.P. (1978) in Atheroclerosis Reviews, Vol. 3, ( Gotto, A.M. and Paoletti, R., Eds.), Raven Press, New York.Google Scholar
  4. 4.
    Inter-Society Commission for Heart Disease Resources. (197U) Circulation 42, A-55-A-95.Google Scholar
  5. 5.
    Goldstein, J.L., and Brown, M.S. (1975) Arch. Pathol. 99, 181184.Google Scholar
  6. 6.
    Rifkind, B.M. (1977) in Atheroclerosis Reviews, Vol. 2, (Gotto, A.M. and Paoletti, R., Eds.), Raven Press, New York, Pp. 67–78.Google Scholar
  7. 7.
    Gordon, T., Castelli, W.P., Hjortland, M.C., Kannel, W.B., and Dawber, T.B. (1977) Am. J. Med. 62, 707.PubMedCrossRefGoogle Scholar
  8. 8.
    Solberg, L.A., and McGarry, P.A. (1972) Atherosclerosis 16, 141–154.PubMedCrossRefGoogle Scholar
  9. 9.
    Hollander, W. (1973) Circulation 48, 1112–1127.PubMedCrossRefGoogle Scholar
  10. 10.
    Gordon, T., and Shurtleff, D. (1973) An Epidemiological Investigation of Cardiovascular Disease, Section 29, DHEW Publication No. (NIH) 74–478, Washington, D.C.Google Scholar
  11. 11.
    The University Group Diabetes Program. (1970) Diabetes 19, Suppl. 2, 787–830.Google Scholar
  12. 12.
    Strong, J.P., and Richards, M.L. (1976) Atheroscl. 23, 451–476.CrossRefGoogle Scholar
  13. 13.
    Gordon, T., Kannel, W.B., McGee, D., and Dawber, T.R. (1974) Lancet 2, 1345–1348.PubMedCrossRefGoogle Scholar
  14. 14.
    Becker, C.G., and Dubin, T. (1977) J. Exp. Med. 146, 457–467.Google Scholar
  15. 15.
    Wagner, W.D., Clarkson, T.B., Feldner, M.A., and Pritchard, R.W. (1973) Exp. Mol. Pathol. 19, 304–319.Google Scholar
  16. 16.
    Paffenbarger, R.S., Jr., and Hale, W.E. (1975) N. Engl. J. Med. 292, 545–550.Google Scholar
  17. 17.
    Jenkins, C.D. (1976) N. Engl. J. Med. 294, 987–994; 1033–1038.Google Scholar
  18. 18.
    Stamler, J., and Epstein, F. (1972) Prov. Med. 1, 27–48.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Henry C. McGillJr.
    • 1
  1. 1.The University of Texas Health Science Center San AntonioUSA

Personalised recommendations