Summary of Workshop 1b: Smooth Muscle

  • W. A. Thomas
  • J. F. Mustard
  • S. Moore
  • M. J. Karnovsky
  • T. P. Bersot
  • H. Wolinsky
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 104)


Atherogenesis is characterized in part by excessive proliferation of arterial intimal smooth muscle cells (SMC). Arterial SMC proliferation can be produced by acute or chronic intimal trauma in normo-lipidemic (NL) animals, especially if the endothelial cells (EC) are denuded as with a balloon catheter. Also, intimal SMC proliferation can be produced by making animals hyperlipidemic (HL) by dietary manipulation without trauma to the EC.


Smooth Muscle Cell Balloon Catheter Smooth Muscle Cell Proliferation Arterial Smooth Muscle Cell Endothelial Cell Injury 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • W. A. Thomas
    • 1
  • J. F. Mustard
  • S. Moore
  • M. J. Karnovsky
  • T. P. Bersot
  • H. Wolinsky
  1. 1.Department of PathologyAlbany Medical College of Union UniversityNew YorkUSA

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