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Atherosclerosis and Inflammation

  • Isabelle Joris
  • Guido Majno
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 104)

Abstract

It is probably safe to state that atherosclerosis is the sum of several different processes. Each one of the past and current theories of atherosclerosis emphasizes one of these processes. Thus, if we open a contemporary textbook of pathology (1), we find at least four theories: (1) lipid insudation, (b) structural or metabolic alteration of the arterial wall, (c) intimal stress or injury, (d) thrombogenesis or encrustation. To these we should add the two newer theories that emphasize a further aspect of the process, cell proliferation: the theory of Ross et al. (2, 3) which gives platelets the stimulating role, and the theory of Benditt (4, 5) in which the proliferation is considered akin to neoplasia.

Keywords

Arterial Wall Evans Blue Local Accumulation Endothelial Permeability High Cholesterol Diet 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Isabelle Joris
    • 1
  • Guido Majno
    • 1
  1. 1.Department of PathologyUniversity of Massachusetts Medical SchoolWorcesterUSA

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