Atherogenesis: The Process from Normal to Lesion

  • G. C. McMillan
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 104)


Arteriosclerosis is an ancient lesion found in mummies, illustrated by da Vinci and only clearly designated as a disease distinct from aging processes early in this century. (1, 2) The modern period of research, that is, since about 1930, has seen a progressive emphasis on two major theories of atherogenesis.


Lipid Accumulation Fatty Streak Arterial Smooth Muscle Cell Major Theory Endothelial Integrity 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • G. C. McMillan
    • 1
  1. 1.Division of Heart and Vascular Diseases National Heart, Lung and BLood InstituteNational Institutes of HealthBethesdaUSA

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