Immunoglobulins and Antibodies in Pigs

  • Jaroslav Rejnek
  • Ludmila Prokesová


Studies on the ontogenetic development of the antibody response have played an important role in the rapid advances made in immunology during the past fifteen years. Such investigations have permitted a better understanding of the results obtained using adults. This is so because antigenic stimulation in adults results in a response whose level is dependent on the intensity of previous uncontrolled antigenic contacts. In the newborn, on the other hand, the prior antigenic knowledge of an experimental animal can be kept to a minimum or eliminated, thereby allowing a clearer picture of the response.


Light Chain Intestinal Barrier Antibody Activity Newborn Piglet Secretory Component 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. Allen, W. D., and Porter, P. (1970). Immunology 18: 799.PubMedGoogle Scholar
  2. Amoroso, E. C. (1961). Brit. Med. Bull. 17: 81.PubMedGoogle Scholar
  3. Asplund, J. M., Grummer, R. H., and Phillips, P. H. (1962). J. Animal Sci. 21: 412.Google Scholar
  4. Bangham, D. R., Ingram, P. L., Roy, J. H. B., Shillam, K. W. G., and Terry, R. J. (1958). Proc. Roy. Soc. ( London) Ser. B. 149: 184.CrossRefGoogle Scholar
  5. Barrick, E. R., Matrone, G., and Osborne, J. C. (1954). Proc. Soc. Exp. Biol. Med. 87: 92.PubMedGoogle Scholar
  6. Baumstark, J. S. (1968). Arch. Biochem. Biophys. 125: 837.PubMedCrossRefGoogle Scholar
  7. Benacerraf, B., Ovary, Z., Bloch, K. J., and Franklin, E. C. (1963). J. Exp. Med. 117: 937.PubMedCrossRefGoogle Scholar
  8. Berger, R., Ainbender, E., Hodes, H. L., Zepp, H. D., and Hevizy, M. M. (1967). Nature 214: 420.PubMedCrossRefGoogle Scholar
  9. Bloch, K. J., Kourilsky, F. M., Ovary, Z., and Benacerraf, B. (1963). J. Exp. Med. 117: 965. Boorman, K. E., Dodd, B. E., and Gunther, M. (1958). Arch. Diseases Childhood 33: 24.Google Scholar
  10. Boume, F. J. (1969a). Biochim. Biophys. Acta 181: 485.CrossRefGoogle Scholar
  11. Boume, F. J. (1969b). Biochem. Biophys. Res. Commun. 36: 138.CrossRefGoogle Scholar
  12. Bourne, F. J., Pickup, J. and Honour, J. W. (1971a). Biochim. Biophys. Acta 229: 18.PubMedCrossRefGoogle Scholar
  13. Boume, F. J., Honour, J. W., and Pickup, J. (1971b). Immunology 20: 433.Google Scholar
  14. Brambell, F. W. R. (1958). Biol. Rev. Cambridge Phil. Soc. 33: 488.CrossRefGoogle Scholar
  15. Brambell, F. W. R. (1966). Lancet 2: 1087.PubMedCrossRefGoogle Scholar
  16. Brambell, F. W. R., Hemmings, W. A., and Henderson, M. (1951). Antibodies and Embryos, Athlone Press, London.Google Scholar
  17. Brummerstedt-Hansen, E. (1961).Acta Vet. Scand. 2: 254.Google Scholar
  18. Brummerstedt-Hansen, E. (1967). In The Serum Proteins of the Pig. An Immunoelectrophoretic Study, Munksgaard Publ. Co., Copenhagen, p. 85.Google Scholar
  19. Brummerstedt-Hansen, E., and Hirschfeld, J. (1961). Acta Vet. Scand. 7: 317.Google Scholar
  20. Cebra, J. J., and Robbins, J. B. (1966). J. Immunol. 97: 12.PubMedGoogle Scholar
  21. Cerna, J., and Rejnek, J. (1971). Folio Microbiol. (Prague) 16: 535.Google Scholar
  22. Charlwood, P. A., and Thomson, A. (1948). Nature 161: 59.PubMedCrossRefGoogle Scholar
  23. Colacicco, G. (1963). Nature 198: 784.PubMedCrossRefGoogle Scholar
  24. Curtis, J., and Boume, F. J. (1971). Biochim. Biophys. Acta 236: 319.PubMedCrossRefGoogle Scholar
  25. Du Pan, R. M., Wenger, P., Koechli, S., Scheidegger, J. J., and Roux, J. (1959). Clin. Chim. Acta 4: 110.CrossRefGoogle Scholar
  26. Earle, J. P. (1935). J. Agr. Res. 51: 479.Google Scholar
  27. Edelman, G. M., Benacerraf, B., Ovary, Z., and Poulik, M. D. (1961). Proc. Natl. Acad. Sci. U.S. 47: 1751.CrossRefGoogle Scholar
  28. Eriksson, S., and Sjdquist, J. (1960). Biochim. Biophys. Acta 45: 290.PubMedCrossRefGoogle Scholar
  29. Franek, F. (1961). Biochem. Biophys. Res. Commun. 4: 28.PubMedCrossRefGoogle Scholar
  30. Franek, F. (1962). Collection Czech. Chem. Commun. 27: 2808.Google Scholar
  31. Franek, F. (1965). Collection Czech. Chem. Commun. 30: 1947.Google Scholar
  32. Franek, F. (1966). Collection Czech. Chem. Commun. 31: 1142.Google Scholar
  33. Franek, F. (1971). European J. Bioci:em. 19: 176.CrossRefGoogle Scholar
  34. Franek, F., and Keil, B. (1964). Collection Czech. Chem. Commun. 29: 847.Google Scholar
  35. Franek, F., and Lankas, V. (1963). Collection Czech. Chem. Commun. 28: 245.Google Scholar
  36. Franek, F., and Nezlin, R. S. (1963). Biochimija 28: 193.Google Scholar
  37. Franek, F., and Riha, I., (1964), Immunochemistry 1: 49.PubMedCrossRefGoogle Scholar
  38. Franek, F., and Zikân, J. (1964). Collection Czech. Chem. Commun. 29: 1401.Google Scholar
  39. Franek, F., and Zorina, O. M. (1967). Collection Czech. Chem. Commun. 32: 3229.Google Scholar
  40. Franek, F., Riha, I., and Sterzi, J. (1961). Nature 189: 1020.PubMedCrossRefGoogle Scholar
  41. Franek, F., Simek, L., and Kotÿnek, O. (1965). Folia Microbiol. (Prague) 10: 335.CrossRefGoogle Scholar
  42. Franek, F., Keil, B., Novotnj, J., and Sorm, F. (1968). European J. Biochem. 3: 422.CrossRefGoogle Scholar
  43. Franek, F., Keil, B., and Sorm, F. (1969). European J. Biochem. 11: 170.CrossRefGoogle Scholar
  44. Gitlin, D., Kumate, J., Urrusti, J., and Morales, C. (1963). J. Pediat. 63: 871.CrossRefGoogle Scholar
  45. Grey, H. M. (1969). Advan. Immunol. 10: 51.CrossRefGoogle Scholar
  46. Gugler, E., and Muralt, G. von (1959). Schweiz. Med. Wochschr. 89: 925.Google Scholar
  47. Hâjek, P., Kovârú, F., and Kruml, J. (1969). Folia Microbiol. (Prague) 14: 492. Hâjek, P., and Mandel, L. (1971). FoliaMicrobiol. (Prague) 16: 58.CrossRefGoogle Scholar
  48. Halliday, R. (1955). Proc. Roy. Soc. (London) Ser. B 143: 408.CrossRefGoogle Scholar
  49. Halpern, M. S., and Koshland, M. E. (1970). Federation Proc. 29: 2228.Google Scholar
  50. Hanson, L. A., and Johansson, B. G. (1962). Intern. Arch. Allergy Appl. Immunol. 20: 65–79.CrossRefGoogle Scholar
  51. Hemmings, W. A., and Brambell, F. W. R. (1961). Brit. Med. Bull. 17: 96.PubMedGoogle Scholar
  52. Hood, L., Gray, W. R., Sanders, B. G., and Dreyer, W. J. (1967). Cold Spring Harbor Sym. Quant. Biol. 32: 133.CrossRefGoogle Scholar
  53. Jacobsen, P. E., and Monstgaard, J. (1950). Nord. Veterinarmed. 2: 812.Google Scholar
  54. Johnson, P., and Pierce, A. E. (1959). J. Hyg. 57: 309.CrossRefGoogle Scholar
  55. Kabat, E. A. (1939). J. Exp. Med. 69: 103.PubMedCrossRefGoogle Scholar
  56. Carlsson, B. W. (1966a). Acta Pathol. Microbiol. Scand. 67: 83.Google Scholar
  57. Carlsson, B. W. (1966b). Acta Pathol. Microbiol. Scand. 67: 237.Google Scholar
  58. Carlsson, B. W. (1966c). Ph.D. thesis, Studentlitteratur, Lund, Sweden.Google Scholar
  59. Karush, F., and Utsumi, S. (1965). In Molecular and Cellular Basis of Antibody Formation, Proc. of a Symp., Publ. House Czech. Acad. Sci., Prague, p. 145.Google Scholar
  60. Kim, Y. B., Bradley, S. G., and Watson, D. W. (1964). Federation Proc. 23: 346.Google Scholar
  61. Kim, Y. B., Bradley, S. G., and Watson, D. W. (1966). J. Immunol. 97: 52.PubMedGoogle Scholar
  62. Kuttner, A., and Ratner, B. (1923). Am. J. Diseases Children 25: 413.Google Scholar
  63. Lecce, J. G., and Matrone, G. (1960). J. Nutr. 70: 13.PubMedGoogle Scholar
  64. Lecce, J. G., and Morgan, D. O. (1962). J. Nutr. 78: 263.PubMedGoogle Scholar
  65. Lecce, J. G., Matrone, G., and Morgan, D. O. (1961a). Ann. N.Y. Acad. Sci. 94: 250.PubMedCrossRefGoogle Scholar
  66. Lecce, J. G., Matrone, G., and Morgan, D. O. (1961b). J. Nutr. 73: 158.Google Scholar
  67. Mach, J. P., and Pahud, J. J. (1971). J. Immunol. 106: 552.PubMedGoogle Scholar
  68. Mage, R. G., Young, G. O., Rejnek, J., Reisfeld, R. A., Dubiski, S., and Apelia, E. (1970). Protides Biol. Fluids, Proc. Colloq. 17 (1969), p. 215.Google Scholar
  69. Matthaeus, W., Korn, G. (1967). Zentr. Bakt. Paras. Inf. Hygiene 204: 173.Google Scholar
  70. Metzger, H., and Mannik, M. (1964). J. Exp. Med. 120: 765.PubMedCrossRefGoogle Scholar
  71. Metzger, J. J., and Fougereau, M. (1967). C. R. Acad. Sci. Paris 265: 724.Google Scholar
  72. Miler, I., Tlaskalovâ, H., Mandel, L., and Trâvnicek, J. (1968). Folia Microbiol. (Prague) 13: 472.CrossRefGoogle Scholar
  73. Myers, W. L., and Segre, D. (1963). J. Immunol. 91: 697.PubMedGoogle Scholar
  74. Neuhaus, U. (1961). Tierzucht, Züchtungsbiologie 75: 160.CrossRefGoogle Scholar
  75. Niedermeier, W., Kirkland, T., Acton, R. T., and Bennett, J. C. (1971). Biochim. Biophys. Acta 237: 442.PubMedCrossRefGoogle Scholar
  76. Novotnÿ, J., and Franek, F. (1968). FEBS Letters 2: 93.CrossRefGoogle Scholar
  77. Novotnÿ, J., and Franck, F. (1970). FEBS Letters 9: 33.PubMedCrossRefGoogle Scholar
  78. Novotnÿ, J., Franek, F., Keil, B., and Sorm, F. (1969). FEBS Symp. 15: 193.Google Scholar
  79. Novotnÿ, J., Franek, F., and Sorm, F. (1970). European J. Biochem. 14: 309.CrossRefGoogle Scholar
  80. Olsson, B. (1959). Nord. Veterinarmed. 11: 1.Google Scholar
  81. Ovary, Z., Benacerraf, B., and Bloch, K. J. (1963). J. Exp. Med. 117: 951.Google Scholar
  82. Owen, B. D., Bell, J. M., Williams, C. M., and Oakes, R. G. (1961). Can. J. Animal Sci. 41: 236.CrossRefGoogle Scholar
  83. Pahud, J. J., and Mach, J. P. (1970). Immunochemistry 7: 676.CrossRefGoogle Scholar
  84. Payne, L. C., and Marsh, C. L. (1962). J. Nutr. 76: 151.PubMedGoogle Scholar
  85. Porter, P. (1969a), Immunology 17: 617.PubMedGoogle Scholar
  86. Porter, P. (1969b). Biochim. Biophys. Acta 181: 381.PubMedCrossRefGoogle Scholar
  87. Porter, P. (1971). Biochim. Biophys. Acta 236: 664.PubMedCrossRefGoogle Scholar
  88. Porter, P., and Hill, I. R. (1970). Immunology 18: 565.PubMedGoogle Scholar
  89. Porter, P., and Kenworthy, R. (1970). J. Comp. Pathol. Therap. 80: 233.CrossRefGoogle Scholar
  90. Porter, P., and Noakes, D. E. (1969). Biochem. J. 113: 68.Google Scholar
  91. Porter, P., Noakes, D. E., and Allen, W. D. (1970a). Immunology 18: 909.PubMedGoogle Scholar
  92. Porter, P., Noakes, D. E., and Allen, W. D. (1970b). Immunology 18: 245.PubMedGoogle Scholar
  93. Porter, R. R. (1962). In Gelborn, A., and Hirshberg E. (eds.), Symposium on Basic Problems of Neoplastic Disease Columbia University Press, New York, p. 177.Google Scholar
  94. Prokesovâ, L. (1969). Folio Microbiol. (Prague) 14: 82.CrossRefGoogle Scholar
  95. Prokesovâ, L., and Rejnek, J. (1971). Folio Microbiol. (Prague) 16: 476.CrossRefGoogle Scholar
  96. Prokesovd, L., Rejnek, J., Sterzi, J., and Trâvnicek, J. (1969). Folic Microbiol. (Prague) 14: 372.CrossRefGoogle Scholar
  97. Prokesovâ, L., Rejnek, J., Kostka, J., and Trâvnicek, J. (1970a). Folio Microbiol. (Prague) 15: 337.CrossRefGoogle Scholar
  98. Prokesovâ, L., Rejnek, J., Sterzi, J., and Trâvnicek, J. (1970b). In Sterzi, J., and Riha, M. (eds.), Developmental Aspects of Antibody Formation and Structure Academic Press, New York, p. 757.Google Scholar
  99. Prokesovâ, L., Rejnek. J., and Sterzi, J. (1973). In Research in Immunochemistry and Immunobiology, University Park Press, Baltimore, Maryland (in press).Google Scholar
  100. Putnam, F. W., Easley, C. W., and Lynn, L. T. (1962). Biochim. Biophys. Acta 58: 279.PubMedCrossRefGoogle Scholar
  101. Rejnek, J. (1971). In Ambrosius, H., Malberg, K., and Schäffner, H. (eds.), Antigen-Antibody Reactions. Contributions to the IVth Symp. on Immunology of the Gesell-schaft far Allergie und Immunitätsforschung der DDR VEB Gustav Fischer Verlag Jena, p. 69.Google Scholar
  102. Rejnek, J., Skvaril, F., and Dolezal, A. (1960). Cesk. Pediatrie 15: 97.Google Scholar
  103. Rejnek, J., Kotÿnek, O., and Kostka, J. (1965). Folio Microbiol. (Prague) 10: 327.Google Scholar
  104. Rejnek, J., Kostka, J., and Trâvnicek, J. (1966). Folic Microbiol. (Prague) 11: 173.CrossRefGoogle Scholar
  105. Rejnek, J., Kotÿnek, O., and Kostka J. (1967). Folio Microbiol. (Prague) 12: 31.CrossRefGoogle Scholar
  106. Rejnek, J., Trâvnicek, J., Kostka, J., Sterzi, J., and Lanc, A. (1968a). Folio Microbiol. (Prague) 13: 36.CrossRefGoogle Scholar
  107. Rejnek, J., Trâvnicek, J., Lanc, A., and Tlaskalovâ, H. (1968b). lifss. Z. Friedrich-SchillerUniv. Jena, Math. Naturwiss. Reihe 17: 149.Google Scholar
  108. Richardson, A. K., Kelleher, P. C. (1970). Biochim. Biophys. Acta 214: 117.PubMedCrossRefGoogle Scholar
  109. Rouse, B. T., and Ingram, D. G. (1970). Immunology 19: 901.PubMedGoogle Scholar
  110. Rutqvist, L. (1958). Am. J. Vet. Res. 19: 25.PubMedGoogle Scholar
  111. Salajka, E. (1966). Vet. Med. 11: 537.Google Scholar
  112. Schultze, H. E., and Heremans, J. F. (1966). In Molecular Biology of Human Proteins with Special Reference to Plasma Proteins, Vol. I, Elsevier Publ. Co., Amsterdam, p. 529.Google Scholar
  113. Singer, S. J., Wofsy, L., and Good, A. H. (1965). In Molecular and Cellular Basis of Antibody Formation. Proc. of a Symp., Publ. House Czech. Acad. Sci., Prague p. 135.Google Scholar
  114. Sokol, A. (1968). Folio Microbiol. (Prague) 13: 561.Google Scholar
  115. Sokol, A., Rosocha, J., and Milâr, A. (1954). Vet. Casopis 4: 139.Google Scholar
  116. Sokol, A., and Durkovic, V. (1967). Folia Microbiol. (Prague) 12: 411.Google Scholar
  117. Sokol, A., Koppel, Z., Hrusovskÿ, F., and Eisingerovâ, M. (1968). Folio Microbiol. (Prague) 13: 561.Google Scholar
  118. Sokol, A., Jamrichovâ, O., and Hrusovskÿ, F. (1970). Folia Microbiol. (Prague) 15: 233.Google Scholar
  119. Speer, V. C., Brown, H., Quinn, L., and Catron, D. (1959). J. Immunol. 83: 632.PubMedGoogle Scholar
  120. Sterzi, J., and Silverstein, A. M. (1967). Advan. Immunol. 6: 337.CrossRefGoogle Scholar
  121. Sterzi, J., Kostka, J., Riha, I., and Mandel, L. (1960a). Folla Microbiol. (Prague) 5: 29.CrossRefGoogle Scholar
  122. Sterzi, J., Kostka, J., Mandel, L., Riha, I., and Holub, M. (1960b). In Mechanism of Antibody Formation, Proc. of a Symp., Publ. House Czech. Acad. Sci., Prague p. 130.Google Scholar
  123. Sterzi. J., Pesâk, V., Kostka, J., and Jilek, M. (1964). Folla Microbiol. (Prague) 9: 284.CrossRefGoogle Scholar
  124. Sterzi. J., Mandel, L., Miler. I., and Riha, I. (1965). In Molecular and Cellular Basis of Antibody Formation, Proc. of a Symp., Publ. House Czech. Acad. Sci., Prague, p. 351.Google Scholar
  125. Sterzi, J., Rejnek, J., and Trâvnícek, J. (1966). Folla Microbiol. (Prague) 11: 7.CrossRefGoogle Scholar
  126. Surjan, J. (1969). Acta Microbiol. Acad. Sci. Hung. 16: 107.Google Scholar
  127. Thorbecke, G. J., and Van Furth, R. (1967). In Ontogeny of Immunity, University of Florida Press, Gainesville, Florida, p. 173.Google Scholar
  128. Tlaskalovâ, H., Kamarÿtovâ, V., Mandel, L., Prokesovâ, L., Kruml, J., Lanc, A., and Miler, I. (1970a). Folia Biol. (Prague) 16: 177.Google Scholar
  129. Tlaskalovâ, H., Sterzi, J., Hâjek, P., Pospisil, M., Riha, I., Marvanovâ, H., Kamarÿtovâ, V., Mandel, L., Kruml, J., and Kovarü, F. (1970b). In Sterzi, J., and Riha, M. (eds.), Developmental Aspects of Antibody Formation and Structure, Vol. II, Academic Press, New York, p. 767.Google Scholar
  130. Tlaskalovâ, H., Rejnek, J., Trâvnícek, J., and Lanc, A. (1970c). Folla Microbiol. (Prague) 15: 372.CrossRefGoogle Scholar
  131. Tomasi, T. B. Jr., Tan, E. M., Solomon, A., and Prendergast, R. A. (1965). J. Exp. Med. 121: 101.PubMedCrossRefGoogle Scholar
  132. Tomasi, T. B. Jr., and Bienenstock, J. (1968). Advan. Immunol. 9: 2.Google Scholar
  133. Tormo, J., Chordi, A., Rodriguez-Burgos, A., and Diaz, R. (1967). Vet. Rec. 81: 392.PubMedCrossRefGoogle Scholar
  134. Trâvnícek, J., Mandel, L., Lanc, A., and Rüzicka, R. (1966). Cesk. Fysiologie 15: 240.Google Scholar
  135. Trâvnícek, J., and Mandel L. (1971). Folla Microbiol. (Prague) 16: 92.CrossRefGoogle Scholar
  136. Trnka, Z., Sterzi, J., Lanc, A. and Mandel, L. (1959). Giorn. Malatie Infektive Parasitarie, II. Fasc. p. 330.Google Scholar
  137. Vaerman, J. P. (1970). In Studies on IgA Immunoglobulins in Man and Animals, SintalLouvainGoogle Scholar
  138. Vaerman, J. P. (1971). Immunology 21: 443.PubMedGoogle Scholar
  139. Vaerman, J. P., and Heremans, J. F. (1970). Int. Arch. Allergy Appl. Immunol. 38: 561.PubMedCrossRefGoogle Scholar
  140. Vaerman, J. P., Heremans, J. F., and Van Kerckhoven, G. (1969). J. Immunol. 103: 1421.Google Scholar
  141. Vyas, G. N., Levin, A. S., Fudenberg, H. H. (1970). Nature 225: 275.PubMedCrossRefGoogle Scholar
  142. Wellmann, G., and Engel, H. (1963). Zentr. Bakteriol. Parasitenk. 190: 243.Google Scholar
  143. Yamashita, T., Franek, F., Skvaril, F., and Simek, L. (1968). European J. Biochem. 6: 34.CrossRefGoogle Scholar
  144. Zikân, J. (1966). Collection Czech. Chem. Commun. 31: 4260.Google Scholar
  145. Zikân, J., and Sterzi, J. (1967). Nature 214: 1225.PubMedCrossRefGoogle Scholar
  146. Zikân, J., and Kotÿnek, O. (1968). Biopolymers 6: 681.Google Scholar
  147. Zikân, J., Blazek, J., and Cerna, J. (1970). In Sterzl, J., and Riha, M. (eds.), Developmental Aspects of Antibody Formation and Structure, Academic Press, New York, p. 411.Google Scholar

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© Plenum Press, New York 1973

Authors and Affiliations

  • Jaroslav Rejnek
    • 1
  • Ludmila Prokesová
    • 1
  1. 1.Department of Immunology Institute of MicrobiologyCzechoslovak Academy of SciencePragueCzechoslovakia

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