Memory Loss and Its Possible Relationship to Chromosome Changes

  • Lissy F. Jarvik
Part of the Advances in Behavioral Biology book series (ABBI, volume 6)


To establish a plausible relationship between two events as far removed from each other as the microscopic elements of cellular genetics and the psychological variables of mental functioning should be a challenge sufficient in itself. That I agree to participate in a session dealing with “Drug-related Central Nervous System Changes” is a testimony to my temerity, and not an indication that we know anything about the extent to which drugs contribute either to the chromosome changes, or to the intellectual changes we so often see in elderly persons (Jarvik 1971).


Intellectual Functioning Mental Functioning Senile Dementia Chromosome Change Mental Change 
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  1. 1.
    Baltes, P.B., Schaie, K.W. and Nardi, A.H.: Age and experimental mortality in a seven-year longitudinal study of cognitive behavior. Developmental Psychology, 5: 18–26, 1971.CrossRefGoogle Scholar
  2. 2.
    Bettner, L.G., Jarvik, L.F. and Blum, J.E.: Stroop color-word test, non-psychotic organic brain syndrome, and chromosome loss in aged twins. J. Geront, 26: 458–469, 1971.PubMedGoogle Scholar
  3. 3.
    Birren, J.E.: Neural basis of personal adjustment in aging. In: P. From Hansen (Ed.), Age with a future. Copenhagen: Munksgaard, 48–59, 1964.Google Scholar
  4. 4.
    Bloom, A.D., Neriishi, S., Kamada, N. et al.: Cytogenetic investigation of survivors of the atomic bombings of Hiroshima and Nagasaki, Lancet, 2: 672–674, 1966.PubMedCrossRefGoogle Scholar
  5. 5.
    Bloom, A.D., Neriishi, S., Awa, A.A. et al.: Chromosome aberrations in leucocytes of older survivors of the atomic bombings of Hiroshima and Nagasaki, Lancet, 2: 802–805, 1967.CrossRefGoogle Scholar
  6. 6.
    Blum, J.E., Clark, E.T. and Jarvik, L.F.: The New York State Psychiatric Institute Study of Aging Twins. In: Intellectual Functioning in Adults: Psychological and Biological Influences. L.F. Jarvik, C. Eisdorfer, and J.E. Blum (Eds.), New York: Springer, in press.Google Scholar
  7. 7.
    Eisdorfer, C. and Wilkie, F.: The Duke Longitudinal Research Project. In: Intellectual Functioning in Adults: Psychological and Biological Influences. L.F. Jarvik, C. Eisdorfer, and J.E. Blum (Eds.), New York: Springer, in press.Google Scholar
  8. 8.
    Granick, S. and Birren, J.E.: Cognitive functioning of non-survivors: 12 year follow-up of healthy aged. The Eighth International Congress of Gerontology, II: Abstract No. 240, 67, 1969.Google Scholar
  9. 9.
    Jarvik, L.F., Kallmann, F.J., Lorge, I. and Falek,A.: Longitudinal study of intellectual changes in senescent twins. In: C. Tibbits & W. Donahue, (Eds.) Social and Psychological Aspects of Aging. New York: Columbia Univ. Press, 839–859, 1962.Google Scholar
  10. 10.
    Jarvik, L.F.: Survival and psychological aspects of aging in man. In: Aspects of the Biology of Aging. XXI Symposium of the Society for Experimental Biology, Sheffield, England,Symp. Soc. Exp. Biol 21: 463–483, 1967.Google Scholar
  11. 11.
    Jarvik, L.F. Discussion of Judd, L.L., Brandkamp, W.W., and McGlothlin, W.W. Comparison of the chromosomal patterns obtained from groups of continued users, former users, and nonusers of LSD-25. Amer. J. Psychiat., 126: 72–81, 1969.Google Scholar
  12. 12.
    Jarvik, L.F.: Genetic aspects of aging. In: Rossman (Ed.), Clinical Geriatrics, Philadelphia: J.B. Lippincott, 85–105, 1971.Google Scholar
  13. 13.
    Jarvik, L.F. and Cohen, D.: A biobehavioral approach to intellectual changes with aging. C. Eisdorfer and M.P. Lawton (Eds.), Psychological Aspects of Aging,American Psychological Association, Washington, D.C. in press.Google Scholar
  14. 14.
    Jarvik, L.F., Kato, T., Saunders, B. and Moralishvili, E.: LSD and human chromosomes. In Psychopharmacology, D. Efron (Ed.), U.S. Public Health Service (No. 1836), Washington, D.E., 1968.Google Scholar
  15. 15.
    Jarvik, L.F. and Kato, T.: Chromosomes and mental changes in octogenarians: preliminary findings. Brit. J. Psychiat. 115: 1193–1194, 1969.PubMedCrossRefGoogle Scholar
  16. 16.
    Jarvik, L.F. and Kato, T.: Chromosome examinations in aged twins. Amer. J. Human Genetics, 22: 562–573, 1970.Google Scholar
  17. 17.
    Jarvik, L.F., Altshuler, K.Z., Kato, T. and Blumner, B.: Organic brain syndrome and chromosome loss in aged twins. Diseases of the Nervous System, 32: 159–170, 1971.PubMedGoogle Scholar
  18. 18.
    Kato, T. and Jarvik, L.F.: LSD-25 and genetic damage. Diseases of the Nervous System, 30: 42–46, 1969.PubMedGoogle Scholar
  19. 19.
    Kleemeier, R.W.: Intellectual change in the senium. Proceedings of the Social Statistics Section of the American Statistical Association, 5, 290–295, 1962.Google Scholar
  20. 20.
    Nielsen, J.: Chromosomes in senile dementia. Brit. J. Psychiat., 115: 303–309, 1968.CrossRefGoogle Scholar
  21. 21.
    Riegel, F.K., Riegel, R.M. and Meyer, G.: The prediction of retest resisters in research on aging. J. Geront., 23: 370–374, 1968.PubMedGoogle Scholar
  22. 22.
    Sharma, A.K. and Sharma, A.: “Spontaneous and Chemically Induced Breaks,” In G.H. Bourne and J.F. Danielli (Eds.), International Review of Cytology, 10: New York Academic Press, 101–136, 1960.Google Scholar

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© Plenum Press, New York 1973

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  • Lissy F. Jarvik

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