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Factors Involved in the Altered Phosphate Reabsorption During Phosphate Loading in Thyroparathyroidectomized Rats

  • F. Lang
  • H. Oberleithner
  • R. Greger
  • P. Deetjen
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 103)

Abstract

Several investigators (3,4,5,9) observed a decline of renal phosphate reabsorption after prolonged intravenous infusion of phosphate. Similarily high phosphate diets are known to produce phosphaturia and phosphate depletion enhances renal phosphate reabsorption (11,12). The decline of renal phosphate reabsorption during acute or chronic phosphate loading was demonstrated in both, intact and thyroparathyroidectomized (TPTX) rats. Irrespective of the potentially different mechanisms involved in acute and chronic phosphate loading, the kidney appears to be capable to adjust phosphate reabsorption to phosphate input even in the absence of parathyroid hormone.

Keywords

Urinary Flow Rate Plasma Calcium Renal Phosphate Phosphate Reabsorption Plasma Phosphate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • F. Lang
    • 1
  • H. Oberleithner
    • 1
  • R. Greger
    • 1
  • P. Deetjen
    • 1
  1. 1.Physiologisches InstitutUniversität InnsbruckInnsbruckAustria

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