Effect of Dietary Phosphorus Deprivation on Renal Handling of Calcium and Phosphorus
It has been shown (1–6) that chronic Pi deprivation decreases urinary Pi excretion, but increases Ca excretion, suggesting a close relationship between Ca and Pi in renal adaptation to a variation in dietary Pi intake. However, in chronic Pi deprivation, plasma concentrations of Pi and Ca, and filtered loads of these ions are altered. It is therefore difficult to differentiate whether changes in urinary excretion of these ions were due to changes in filtered loads, or due to changes in tubular reabsorption of these ions independent of filtered loads.
KeywordsTubular Reabsorption Renal Handling Filter Load Renal Adaptation Renal Tubular Effect
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