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The Effect of PTE Infusion in Hypomagnesemic States

  • M. Díaz Curiel
  • J. M. Castrillo
  • A. Rapado
  • P. Esbrit
  • M. Serrano
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 103)

Abstract

The disorders of the parathyroid glands are probably the most frequent cause of hypocalcemia seen in hypomagnesemic states (1,2). The mechanisms reported in the literature are diverse: A) a defect in the secretion and/or formation of parathormone whose assessment by radioimmunoassay (iPTH) shows low serum levels, either absolute or relative to the degree of hypocalcemia (1, 3–5), and B) a failure in the peripheral action of the hormone (shown by the rise in iPTH) (6, 7) on the bone (8) and on the kidney, demonstrated by a deficient tubular response to the action of a parathyroid extract (PTE) (6, 9–11), measured by the tubular reabsorption of phosphate (TRP) and/or by the urinary excretion of cAMP.

Keywords

Parathyroid Hormone Serum Magnesium Peripheral Action Serum Magnesium Level Parathyroid Gland Function 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • M. Díaz Curiel
    • 1
  • J. M. Castrillo
    • 1
  • A. Rapado
    • 1
  • P. Esbrit
    • 1
  • M. Serrano
    • 1
  1. 1.Unidad Metabólica, Fundación Jiménez DíazUniversidad Autónoma de MadridSpain

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