Advertisement

Renal Handling of Phosphate in Very Low Birthweight (VLBW) Infants (<1.3 kg): Effects of Calcium and Sodium Intake

  • I. C. Radde
  • R. F. Cifuentes
  • G. W. Chance
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 103)

Abstract

In an extensive study of mineral requirements of very low birthweight (VLBW) infants we have examined in detail various aspects of phosphorus (P)-homeostasis, such as the effect of a higher (by 50%) P-intake on the renal clearance of phosphorus (Cp) and various indices of parathyroid function. This report deals with the effects of various intakes of calcium (ranging from 100 to 250 mg/kg/24 h) and of sodium (1,5 and 3.0 mEq/kg/24 h) on the Cp and urinary excretion of P (UP) in rapidly growing VLBW infants. The purpose of the study was to determine the Cp in infants (a) on a prolonged “low” Ca intake (100 mg/kg/24 h); (b) the effect of calcium supplementation to a total daily Ca-intake of 175, 210, or 250 mg/kg; and (c) the effect of Na-supplementation.

Keywords

Calcium Intake Accretion Rate Renal Handling VLBW Infant Calcium Lactate 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    Hey, E.: Thermal neutrality. Br.Med.Bull. 31: 69–74 (1975).PubMedGoogle Scholar
  2. 2.
    Gomori, G.: A modification of the colorimetric phosphorus determination for use with the photoelectric colorimeter. J. Lab. Clin. Med. 27: 955 (1942).Google Scholar
  3. 3.
    McCrory, W.W.: Developmental Nephrology. Harvard University Press, Cambridge, Mass. (1972).Google Scholar
  4. 4.
    Edelmann, C.M., Jr.,and Spitzer, A.: J. Pediat. 75: 509–519 (1969).CrossRefGoogle Scholar
  5. 5.
    Nash, M.A. and Edelmann, C.M., Jr.: Nephron 11: 71–90 (1973).CrossRefGoogle Scholar
  6. 6.
    Cifuentes, R.F., Radde, I.C., Chance, G.W.: Programme 6th Parathyroid Conference Vancouver, Canada, 1977,p.144.(Abstract).Google Scholar
  7. 7.
    Potter, E.L. and Thierstein, S.T.: J. Pediat. 22: 695 (1943).CrossRefGoogle Scholar
  8. 8.
    Roy, R., Chance G.W., Radde, I.C., Hill, D.E., Willis, D.M.,and Sheepers, J.: Pediat.Res. 10: 526–531 (1976).PubMedCrossRefGoogle Scholar
  9. 9.
    Schneider, E.G., Strandhoy, J.W., Willis, L.R. and Knox, F.G.: Kidney Int. 4: 369 (1973).Google Scholar
  10. 10.
    Schryner, H.F., Hintz, H.F. and Craig, P.H.: J. Nutr. 101: 1257 (1971).Google Scholar
  11. 11.
    Clark, I.: Am.J. Physiol. 217: 871 (1969).PubMedGoogle Scholar
  12. 12.
    Hövels, O., Thilenius, O.G.,and Krafczyk, S.: Z. Kinderheilk. 83: 508 (1960).CrossRefGoogle Scholar
  13. 13.
    Amiel, C., Kuntziger, H., Couette, S., Coureau, C., and Bergounioux, N.:J. Clin. Invest. 57: 256–263 (1976).PubMedCrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • I. C. Radde
    • 1
  • R. F. Cifuentes
    • 1
  • G. W. Chance
    • 1
  1. 1.Research Institute, Div. Perinatology & EndocrinologyThe Hospital for Sick ChildrenTorontoCanada

Personalised recommendations