Renal Handling of Phosphate in Very Low Birthweight (VLBW) Infants (<1.3 kg): Effects of Calcium and Sodium Intake

  • I. C. Radde
  • R. F. Cifuentes
  • G. W. Chance
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 103)


In an extensive study of mineral requirements of very low birthweight (VLBW) infants we have examined in detail various aspects of phosphorus (P)-homeostasis, such as the effect of a higher (by 50%) P-intake on the renal clearance of phosphorus (Cp) and various indices of parathyroid function. This report deals with the effects of various intakes of calcium (ranging from 100 to 250 mg/kg/24 h) and of sodium (1,5 and 3.0 mEq/kg/24 h) on the Cp and urinary excretion of P (UP) in rapidly growing VLBW infants. The purpose of the study was to determine the Cp in infants (a) on a prolonged “low” Ca intake (100 mg/kg/24 h); (b) the effect of calcium supplementation to a total daily Ca-intake of 175, 210, or 250 mg/kg; and (c) the effect of Na-supplementation.


Calcium Intake Accretion Rate Renal Handling VLBW Infant Calcium Lactate 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • I. C. Radde
    • 1
  • R. F. Cifuentes
    • 1
  • G. W. Chance
    • 1
  1. 1.Research Institute, Div. Perinatology & EndocrinologyThe Hospital for Sick ChildrenTorontoCanada

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