Abstract
With the almost complete disappearance of vitamin D deficiency in the North-American continent, most cases of rickets now encountered on the pediatric wards may be attributed to one of the several states of vitamin D resistance. The most common of them is familial hypophosphatemic rickets (FHR) a condition usually transmitted as a sex-linked dominant trait. It is characterized by a hypophosphatemia present at birth, bone changes resembling vitamin D deficiency rickets and growth retardation. Bony deformities of the lower limbs are frequent but myopathy is strikingly absent (1).
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© 1978 Plenum Press, New York
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Glorieux, F.H., Bordier, P.J., Marie, P., Delvin, E.E., Travers, . (1978). Inadequate Bone Response to Phosphate and Vitamin D in Familial Hypophosphatemic Rickets (FHR). In: Massry, S.G., Ritz, E., Rapado, A. (eds) Homeostasis of Phosphate and Other Minerals. Advances in Experimental Medicine and Biology, vol 103. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7758-0_25
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DOI: https://doi.org/10.1007/978-1-4684-7758-0_25
Publisher Name: Springer, Boston, MA
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