Effect of Volume Expansion on Phosphate Transport in Uremic Dogs

  • Sung-Feng Wen
  • James W. BoynarJr.
  • Robert W. Stoll
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 103)


Functional adaptation for renal phosphate transport in chronic renal failure has generally been considered to be mainly the result of secondary hyperparathyroidism (1, 2). On the other hand, it has also been reported that uremic animals can maintain phosphate homeostasis in the absence of parathyroid glands (3). Our present clearance and micropuncture studies were designed to re-evaluate the role of parathyroid hormone (PTH) in phosphate adaptation of uremic remnant kidney dogs.


Proximal Tubule Parathyroid Gland Secondary Hyperparathyroidism Functional Adaptation Phosphate Transport 
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Copyright information

© Plenum Press, New York 1978

Authors and Affiliations

  • Sung-Feng Wen
    • 1
  • James W. BoynarJr.
    • 1
  • Robert W. Stoll
    • 1
  1. 1.Department of MedicineUniversity of Wisconsin Center for Health SciencesMadisonUSA

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