Advertisement

Treatment of Malignant Neoplasms with Radiofrequency Hyperthermia — Clinical Experience

  • Z. Dreznik
  • R. E. Falk
  • U. Ambus
  • V. Howard
  • D. Venturi
  • L. Makowka

Abstract

The use of ‘heat’ for the treatment of malignant neoplasms was mentioned in the medical literature as early as the 19th century.1 This subject remained unnoticed and it was only in the last decade when better and safer equipment became available, that this treatment modality gained a renewed interest.

Keywords

Liver Metastasis Obstructive Jaundice Alkaline Phosphatase Level Hyperthermia Treatment Superficial Tumor 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

Preview

Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.

References

  1. 1.
    W. B. Coley, The treatment of malignant tumors by repeated innoculations of erysipelas with a report of original cases, Am. J. Med. 105: 487 (1893).CrossRefGoogle Scholar
  2. 2.
    G. Jr. Crile, Heat as an adjunct to the treatment of cancer: experimental studies, Cleveland Clin. Quart. 28: 75 (1961).Google Scholar
  3. 3.
    D. S. Muckle, J. A. Dickson, The selective inhibitory effect of hyperthermia on the metabolism and growth of malignant cells, Brit. J. Cancer 15: 771 (1978).Google Scholar
  4. 4.
    P. M. Gullino, F. H. Grantham, Studies on the exchange of fluids between host and tumor. II. The blood flow of hepatomas and other tumors in rats and mice, J. Natl. Cancer Inst. 27: 1465 (1961).Google Scholar
  5. 5.
    J. A. Dickson, S. A. Shah, Technology for the hyperthermia treatment of large solid tumors at 50°C, Clin. Oncol. 3: 301 (1977).Google Scholar
  6. 6.
    E. Bender, T. Schramm, Untersuchungen sur thermosensibilitat von tumor and normalzellen in vitro, Acta Biol. Med. Germ. 17: 527 (1966).Google Scholar
  7. 7.
    J. B. Marmor, Interaction of hyperthermia and chemotherapy in animals, Cancer Res. 39: 2269 (1979).Google Scholar
  8. 8.
    G. M. Hahn, J. Braun, I. Har-Kedar, Thermochemotherapy: synergism between hyperthermia (42°C - 430C) and Adriamycin (or Bleomycin) in mammalian cell inactivation, Proc. Natl. Acad. Sci. USA 72: 937 (1975).CrossRefADSGoogle Scholar
  9. 9.
    J. A. Dickson, H. A. Ellis, The influence of tumor volume and the degree of heating on the response of the solid Yoshida sarcoma to hyperthermia (40°C - 42°C), Cancer Res. 36: 1188 (1976).Google Scholar

Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Z. Dreznik
    • 1
  • R. E. Falk
    • 1
  • U. Ambus
    • 1
  • V. Howard
    • 1
  • D. Venturi
    • 1
  • L. Makowka
    • 1
  1. 1.Goldie Rotman Oncology Unit and the Department of Surgery Toronto General HospitalFaculty of Medicine, University of TorontoTorontoCanada

Personalised recommendations