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Carbohydrate Metabolism in African Trypanosomes, with Special Reference to the Glycosome

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Book cover Carbohydrate Metabolism in Cultured Cells

Abstract

Over the last decade, our knowledge of the biochemistry and molecular biology of trypanosomes has expanded so much that the African trypanosome, Trypanosoma brucei, is now the equivalent of E. coli to the biochemical parasitologist. Trypanosomes are of interest to scientists not only because of their medical and veterinary importance, but also because of several unique features of their biochemistry and molecular biology. Two such features have been reviewed recently: the mitochondrial DNA network (the kinetoplast) and its role in the life cycle (Hajduk, 1978; Borst and Hoeijmakers, 1979; Barker, 1980; Englund et al., 1982), and the variant surface glycoprotein and its role in evading the immune response of the host (Englund et al., 1982; Turner, 1982).

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  1. Laboratory of Medical Biochemistry, The Rockefeller University, New York, New York, 10021, USA

    Alan H. Fairlamb

  2. Research Institute for Tropical Diseases, International Institute for Cellular and Molecular Pathology, B-1200, Brussels, Belgium

    Fred R. Opperdoes

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  1. Department of Biochemistry, University of Leicester, LE1 7RH, Leicester, England, UK

    Michael J. Morgan

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Fairlamb, A.H., Opperdoes, F.R. (1986). Carbohydrate Metabolism in African Trypanosomes, with Special Reference to the Glycosome. In: Morgan, M.J. (eds) Carbohydrate Metabolism in Cultured Cells. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7679-8_6

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