Disorders of Lipid and Lipoprotein Metabolism

  • DeWitt S. Goodman


It is the aim of this chapter to review the major advances that occurred during 1975 with regard to our knowledge about the metabolism of the major plasma lipids and lipoproteins, and about clinical abnormalities in lipid transport, with particular emphasis on the hyperlipidemias. In addition, some recent major developments that occurred before 1975 will be reviewed briefly in order to provide important background information. The well-established association between the presence of hyperlipidemia and an increased risk of the development of coronary heart disease (Kannel et al., 1961, 1971; Carlson and Böttiger, 1972) has served to stimulate both biochemists and clinicians to focus considerable research efforts on this area.


Familial Hypercholesterolemia Lipoprotein Metabolism Familial Hypercholesterolemia Cholesterol Acyltransferase Portacaval Shunt 
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Copyright information

© Plenum Publishing Corporation 1976

Authors and Affiliations

  • DeWitt S. Goodman
    • 1
  1. 1.Department of MedicineCollege of Physicians and Surgeons of Columbia UniversityNew YorkUSA

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