Influence of Four Commercial Sensitivity Media on in Vitro Activity of Several Antibiotics
MIC’s and inhibition zones of six antibiotics were determined simultaneously on four commercially available sensitivity test media, by means of standardized procedures. Multiple strains of several bacterial genera were used. Two media proved to be unsuitable for tetracycline and aminoglycoside testing respectively; on one of them, most E. coli strains would be interpreted as being resistant to tetracycline; on the other, most gramnegative rods were marginally sensitive or resistant to the aminoglycosides.These data and other details on differences between the media investigated are discussed in the light of the requirements with regard to performance.
KeywordsInhibition Zone Proteus Mirabilis Vitro Activity Inhibition Zone Diameter Normal Human Plasma
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