Pharmacokinetics and Ototoxicity of Gentamicin, Tobramycin and Amikacin
The aim of this paper is to give a survey of the pharmacokinetical studies on the ototoxicity of the new aminoglycoside antibiotics Gentamicin, Tobramycin and Amikacin. The animal used was the guinea pig and the antibiotic concentrations were determined by the microbiological method (Bac subtilis ATCC 6633).
KeywordsToxicity Gentamicin Aminoglycoside Uremia Amikacin
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