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New Data on Pharmacology of Gentamycin

  • D. Zhelyazkov
  • K. Ivanova
  • N. Gueorguiev
  • R. Marinova
  • A. Beltcheva
  • M. Mangurova
  • N. Temnyalov
Part of the Chemotherapy book series (CT, volume 2)

Abstract

During the last eight years we have carried out a detailed study of the pharmacology and toxicology of gentamycin, produced in Bulgaria. It included investigations of the acute, subacute and chronic toxicity of the antibiotic; observations on the sex and species differences in its toxicology; comparison of its acute toxicity with those of the other aminoglycoside antibiotics (8, 9); study of its influence on the normal microbial flora of the macro-organism (6), of its relation to the mineral metabolism (5); elucidation of its action on the blood pressure (2), intestinal smooth musculature (2), myoneural synapses of the skeletal muscles (3), as well as its direct effect on the striated musculature and muscle fatigue (7) and many others.

Keywords

Minimum Inhibitory Concentration Minimum Inhibitory Concentration Amino Sugar Intestinal Smooth Musculature Direct Electrical Stimulation 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • D. Zhelyazkov
    • 1
  • K. Ivanova
    • 1
  • N. Gueorguiev
    • 1
  • R. Marinova
    • 1
  • A. Beltcheva
    • 1
  • M. Mangurova
    • 1
  • N. Temnyalov
    • 1
  1. 1.Department of PharmacologyMedical FacultyVarnaBulgaria

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