Experimental Intra-Abdominal Sepsis

  • J. G. Bartlett
  • A. B. Onderdonk
  • T. Louie
  • S. L. Gorbach
Part of the Chemotherapy book series (CT, volume 2)


Intra-abdominal sepsis usually involves multiple different bacterial species derived from the normal colonic flora. In most instances both aerobes and anaerobes are present, and the problem is to determine which of the several constituents represent true pathogens. Are these to be considered aerobic or anaerobic infections? Alternatively, there may be bacterial synergy in which both microbial types are contributing to the pathologic events. These distinctions have important implications in the area of chemotherapeutics. For practical clinical purposes, a key question concerns the necessity to treat all microbial components at the infected site. If selective antimicrobial therapy is possible, which microorganisms should receive the thrust of the attack?


Intraabdominal Abscess Bacteroides Fragilis Hemolytic Streptococcus Neomycin Sulfate Sterile Beaker 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • J. G. Bartlett
    • 1
  • A. B. Onderdonk
    • 1
  • T. Louie
    • 1
  • S. L. Gorbach
    • 2
  1. 1.Infectious Disease ServiceVeterans Administration HospitalBostonUSA
  2. 2.Tufts-New England Medical CenterBostonUSA

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