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The Assay of Serum Aminoglycoside Concentrations by the (14C)-Acetyl Transferase Technique

  • J. M. Broughall
  • D. S. Reeves
Part of the Chemotherapy book series (CT, volume 2)

Abstract

The recently introduced technique of labelled group transfer (1–3) for the assay of serum gentamicin concentrations enables hospital laboratories with suitable radioisotope measuring equipment, i.e., a liquid scintillation counter for β radiation, to offer a quicker and more accurate service than that possible with traditional agar plate diffusion methods, especially when the acetyl transferase technique is used (3).

Keywords

Aminoglycoside Antibiotic Cyanogen Bromide Acetyl Coenzyme Washed Cell Suspension Serum Gentamicin Concentration 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

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    Ten Krooden, E., and J.H. Darrel, (1974). J.Clin.Path. 27, 452–456.Google Scholar
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    Phillips, I., C. Warren and S.E. Smith, (1974). J.Clin.Path. 27, 447–451.PubMedCrossRefGoogle Scholar
  3. 3.
    Broughall, J., and D.S. Reeves, (1975). J.Clin.Path. 28, 140–145.PubMedCrossRefGoogle Scholar
  4. 4.
    Davies, J., M. Brzezinska and R. Benveniste, (1971). Annals New York Acad. Sci., 128, 226–233.Google Scholar
  5. 5.
    Reeves, D.S., and H.A. Holt, (1975). J.Clin.Path. 28, 435–442.PubMedCrossRefGoogle Scholar

Copyright information

© Springer Science+Business Media New York 1976

Authors and Affiliations

  • J. M. Broughall
    • 1
  • D. S. Reeves
    • 1
  1. 1.Dept. of Medical MicrobiologySouthmead General HospitalBristolEngland

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