Environmental Induction of Teleost Cytochrome P-450 Detected by Immunochemical Analysis
Organic foreign compounds have been recognized as having worldwide distribution. Polychlorinated biphenyls, for example, are found in regions extending from the atmosphere (Atlas and Giam, 1981) to the deep sea (Stegeman et al., 1986). In some estuaries and coastal waters there are local high concentrations of these and other compounds that possess biological activity. The significance of such compounds in the sea is not yet known, but may be disclosed by studies on mechanisms of their biological action and transformation. Many such compounds are transformed by oxidative metabolism to products that are either more reactive or less reactive than the parent compound.
KeywordsHepatic Cytochrome Polynuclear Aromatic Hydrocarbon Marine Teleost Polycyclic Hydrocarbon English Sole
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