Environmental Induction of Teleost Cytochrome P-450 Detected by Immunochemical Analysis

  • John J. Stegeman
Conference paper
Part of the Lecture Notes on Coastal and Estuarine Studies book series (COASTAL, volume 25)


Organic foreign compounds have been recognized as having worldwide distribution. Polychlorinated biphenyls, for example, are found in regions extending from the atmosphere (Atlas and Giam, 1981) to the deep sea (Stegeman et al., 1986). In some estuaries and coastal waters there are local high concentrations of these and other compounds that possess biological activity. The significance of such compounds in the sea is not yet known, but may be disclosed by studies on mechanisms of their biological action and transformation. Many such compounds are transformed by oxidative metabolism to products that are either more reactive or less reactive than the parent compound.


Hepatic Cytochrome Polynuclear Aromatic Hydrocarbon Marine Teleost Polycyclic Hydrocarbon English Sole 
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Copyright information

© Springer-Verlag New York, Inc. 1988

Authors and Affiliations

  • John J. Stegeman
    • 1
  1. 1.Biology Department Woods HoleOceanographic InstitutionWoods HoleUSA

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