A Possible Role for Thyrotropin Releasing Hormone (TRH) in Antidepressant Treatment

  • Albert Sattin
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 221)


TRH is a tripeptide which was discovered in the context of hypothalamic-thyroid function but which is now known to be widely distributed throughout the CNS (Jackson, 1982). The majority of TRH in the CNS is extrahypothalamic and its regional concentrations are highly variant (Kubek et al., 1977).


Antidepressant Treatment Antidepressant Effect Thyrotropin Release Hormone Lumbar Spinal Cord Electroconvulsive Shock 


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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • Albert Sattin
    • 1
  1. 1.R. L. Roudebush V. A. Medical Center, Indianapolis and Institute of Psychiatric ResearchIndiana University Medical CenterIndianapolisUSA

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