Molecular Mechanisms of Neuronal Excitability: Possible Involvement of CaM Kinase II in Seizure Activity

  • William C. Taft
  • James R. Goldenring
  • Robert J. DeLorenzo
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 221)


An understanding of the molecular mechanisms that underlie neuronal responsiveness is an important goal of contemporary neuroscience. The specific biochemical events that modulate excitability of neurons and neuronal systems will provide important insights into the complex regulatory mechanisms of the nervous system. In the clinical neurosciences, an understanding of these molecular events may provide significant avenues for the development of treatment protocols for diseases of the nervous system.


Neuronal Excitability Dependent Protein Kinase Postsynaptic Density Calmodulin Binding Protein Hippocampal Membrane 
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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • William C. Taft
    • 1
  • James R. Goldenring
    • 2
  • Robert J. DeLorenzo
    • 1
  1. 1.Departments of Neurology and PharmacologyMedical College of Virginia - VCURichmondUSA
  2. 2.Department of SurgeryYale University School of MedicineNew HavenUSA

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