Regulation of Neuronal Adenylate Cyclase

  • M. M. Rasenick
  • M. M. Marcus
  • Y. Hatta
  • F. DeLeon-Jones
  • S. Hatta
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 221)


Receptors for a panoply of neurotransmitters and neuromodulators are known to couple to the adenylate cyclase system. In the past few years we have benefitted from an explosion of information concerning the molecular identification of the adenylate cyclase components, and this information has served both to elucidate possible mechanisms for the coupling of adenylate cyclase to receptors as well as the activation cascade of that enzyme. This information has also served to illustrate the extraordinary complexity of the system. Several recent reviews (cf. Birnbaumer et al., 1985; Gilman, 1984) have addresssed the structure and function of adenylate cyclase. The purpose of this manuscript is not to overlap with those, but rather, to illustrate some of the unusual features of adenylate cyclase from neural systems.


Adenylate Cyclase Adenylate Cyclase Activity Synaptic Membrane Adenylate Cyclase System Basal Adenylate Cyclase Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • M. M. Rasenick
    • 1
  • M. M. Marcus
    • 1
  • Y. Hatta
    • 1
  • F. DeLeon-Jones
    • 1
    • 2
  • S. Hatta
    • 1
  1. 1.Department of Physiology and BiophysicsUniversity of Illinois College of MedicineChicagoUSA
  2. 2.Westside VA HospitalChicagoUSA

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