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Regulation of Intracellular Thyroid Hormone Concentrations in the Fetus

  • Maria Jesús Obregón
  • Carmen Ruiz de Oña
  • Francisco Escobar del Rey
  • Gabriella Morreale de Escobar
Part of the NATO ASI Series book series (NSSA, volume 161)

Abstract

Thyroid hormones play an important role in development1, especially in brain development2, 3. The role of thyroid hormones in development include the stimulation of skeletal maturation, the diferentiation of central nervous system, and they seem to regulate other processes such as the maturation of lung and the process of non-shivering thermogenesis in the neonate. Most of the information available is based on experimental models, mainly in the rat and sheep, due to the obvious difficulties to examine the effects of thyroid hormone deficiency in the human developing brain.

Keywords

Thyroid Hormone Brown Adipose Tissue Fetal Brain Congenital Hypothyroidism Fetal Plasma 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Maria Jesús Obregón
    • 1
  • Carmen Ruiz de Oña
    • 1
  • Francisco Escobar del Rey
    • 1
  • Gabriella Morreale de Escobar
    • 1
  1. 1.Unidad de Endocrinología Experimental, Instituto de Investigaciones BiomédicasC.S.I.C., Facultad de MedicinaMadridSpain

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