Neurological Development in Congenital Hypothyroidism
Neonatal screening for hypothyroidism was instituted to improve the mental prognosis, which was previously unsatisfactory. Since 1975’ early diagnosis and treatment have been possible in Europe thanks to screening. Over 10 years later, several studies2–4 indicate that mental development is normal. However, neurological dysfunction involving the cerebellum has been reported. These abnormalities, which had been described before the institution of screening5–8 and which constituted a supplementary handicap, seem to be present only to a minor degree in detected hypothyroid children. We therefore carried out a detailed neurological study in order to discover the importance of these neurological impairments, their correlation with other factors of gravity and the effectiveness of assistance in improving school achievement.
KeywordsIntelligence Quotient Congenital Hypothyroidism Neonatal Screening Neurological Development Bone Maturation
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