Resistance to Thyroid Hormones and Screening for High Thyroxine at Birth

  • Samuel Refetoff
  • Myriam Charbonneau
  • David H. Sarne
  • Junta Takamatsu
  • Jean H. Dussault
Part of the NATO ASI Series book series (NSSA, volume 161)


Resistance to thyroid hormone encompasses a heterogeneous group of conditions characterized by reduced responses of target tissues to a supply of thyroid hormone which under normal circumstances would be excessive. The defects have always been partial, because if complete, they would probably be incompatible with life.


Thyroid Hormone Thyrotropin Release Hormone Congenital Hypothyroidism Culture Skin Fibroblast Thyroid Hormone Action 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Samuel Refetoff
    • 1
  • Myriam Charbonneau
    • 2
  • David H. Sarne
    • 1
  • Junta Takamatsu
    • 1
  • Jean H. Dussault
    • 2
  1. 1.Departments of Medicine and PediatricsThe University of ChicagoChicagoUSA
  2. 2.Laval University School of Medicine and the Quebec Network of Genetic MedicineCanada

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