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Congenital Defects Associated with Congenital Hypothyroidism

  • John Lazarus
  • Ieuan Hughes
  • Peter Harper
  • Stephen Bamforth
Part of the NATO ASI Series book series (NSSA, volume 161)

Abstract

Congenital hypothyroidism (CH) has an incidence of about 1 in 4000 live births.l The aetiology of the condition is poorly understood although it is recognised that athyreosis occurs in approximately 30% of infants and various degrees of ectopia of the thyroid gland in the remaining cases.2 In 1986 we reported that 20% of a group of CH infants identified in one screening programme had congenital malformation in addition to CH.3 In view of this finding and a confirmatory report from one centre in the USA4 we have attempted to establish the possible relationship between CH and congenital defects worldwide.

Keywords

Congenital Malformation Spina Bifida Marfan Syndrome Congenital Hypothyroidism Urinary Iodine 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • John Lazarus
    • 2
  • Ieuan Hughes
    • 1
  • Peter Harper
    • 2
  • Stephen Bamforth
    • 2
  1. 1.Department of PaediatricsUniversity of Wales College of MedicineCardiffWales
  2. 2.Department of MedicineUniversity of Wales College of MedicineCardiffWales

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