Placental Transfer of Substances from Mother to Fetus Affecting Fetal Pituitary-Thyroid Function

  • Lewis E. Braverman
Part of the NATO ASI Series book series (NSSA, volume 161)


Over the past years, especially since screening programs for the detection of congenital hypothyroidism have been established, a great deal of interest has centered on the placental transfer of hormones and drugs which might affect fetal thyroid function. Drs. Morreale de Escobar and Emèrson will discuss in detail the possible transfer of thyroid hormones from mother to fetus and the role of the placenta in fetal thyroid homeostasis. The present discussion will focus on studies carried out in collaboration with Dr. Elio Roti from the University of Parma, Parma, Italy and investigators in my laboratory, all related to the transplacental passage of a variety of substances known to affect adult hypothalamic-pituitary-thyroid function (Table 1).


Cord Blood Congenital Hypothyroidism Antithyroid Drug Transplacental Passage Thyroid Stimulate Immunoglobulin 
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Copyright information

© Plenum Press, New York 1989

Authors and Affiliations

  • Lewis E. Braverman
    • 1
  1. 1.University of Massachusetts School of MedicineWorcesterUSA

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