Prospects with Multifactorial Approaches Emphasizing Improvement in Life Style

  • Jeremiah Stamler
  • David M. Berkson
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 26)


Ability to Reduce the Current High Mortality Rates from Premature Heart Attack in the U. S.A. — Evidence from International Studies


Coronary Heart Disease Coronary Risk Factor Coronary Heart Disease Prevention Premature Coronary Heart Disease Multifactorial Approach 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.


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  1. 1.
    Arteriosclerosis--Report by National Heart and Lung Institute Task Force on Arteriosclerosis, Vol. I, U.S. Department of Health, Education, and Welfare Public Health Service, DHEW Pub. No. (NIH) 72–137, Washington, D.C., June (1971).Google Scholar
  2. 2.
    Stamler, J., R. Stamler, and R. B. Shekelle, in Ischaemic Heart Disease. (Eds.) J. H. deHaas, H. C. Hemker, and H. A. Snellen, Leiden University Press, Leiden, the Netherlands (1970) p. 84.CrossRefGoogle Scholar
  3. 3.
    Keys, A. Circulation 41: Suppl. 1 (1970).Google Scholar
  4. 4.
    Atherosclerosis Study Group and Epidemiology Study Group--Report of Inter-Society Commission for Heart Disease Resources. Circulation 42: A55 (1970).Google Scholar
  5. 5.
    Stamler, J. Lectures on Preventive Cardiology, Grune and Stratton, New York, N.Y. (1967).Google Scholar
  6. 6.
    Stamler, J., D. M. Berkson, and H. A. Lindberg, in Pathogenesis of Atherosclerosis. (Eds.) R. W. Wissler and J. C. Geer, Williams and Wilkins, Baltimore, Md. (1972) in press.Google Scholar
  7. 7.
    Data from the Pooling Project, Council on Epidemiology, American Heart Association -- a national cooperative project for pooling data from the Albany civil servant, Chicago People’s Gas Company, Chicago Western Electric Company, Framingham community, Los Angeles civil servant, Minneapolis-St. Paul business men, and other prospective epidemiologic studies of adult cardiovascular disease in the United States. The following are representative references (8–19) on the individual studies and on the results of the Pooling Project to date.Google Scholar
  8. 8.
    Doyle, J. T. New York J. Med. 63: 1317 (1963).Google Scholar
  9. 9.
    Stamler, J. Amer. J. Cardiol. 10: 319 (1962).PubMedCrossRefGoogle Scholar
  10. 10.
    Paul, O., M. H. Lepper, W. H. Phelan, G.W. Dupertuis, A. MacMillan, H. McKean, and H. Park. Circulation 28: 20 (1963).PubMedCrossRefGoogle Scholar
  11. 11.
    Dawber, T. R., W. B. Kannel, and P.M. McNamara. Trans. Assoc. Life Insur. Med. Dir. Amer. 47: 70 (1964).Google Scholar
  12. 12.
    Chapman, J. M. and F. J. Massey. J. Chron. Dis. 17: 933 (1964).PubMedCrossRefGoogle Scholar
  13. 13.
    Keys, A., H. L. Taylor, H. Blackburn, J. Brozek, J. T. Anderson, and E. Simonson. Circulation 28: 381 (1963).PubMedCrossRefGoogle Scholar
  14. 14.
    Moore, F. E. Conf. on Cardiovasc. Disease Epidemiology, Council on Epidemiology, Amer. Heart Assn., New Orleans, Louisiana, March (1969).Google Scholar
  15. 15.
    Doyle, J. T. and S.H. Kinch. Amer. Heart Assn., 42nd Scientific Sessions, November (1969).Google Scholar
  16. 16.
    Epstein, F. H. and F. E. Moore. Progress Report to Natl. Heart Inst. on the Natl. Cooperative Pooling Project (1968).Google Scholar
  17. 17.
    Paul, O. Brit. Heart J. 33: (Suppl.) 116 (1971).PubMedCrossRefGoogle Scholar
  18. 18.
    Doyle, J. T. and W.B. Kannel. VI World Congress of Cardiology, London, England, September (1970).Google Scholar
  19. 19.
    Berkson, D. M., J. Stamler, H. A. Lindberg, W. A. Miller, E.L. Stevens, R. Soyugenc, T. J. Tokich, and R. Stamler, in Atherosclerosis, Second International Symp. (Ed.) R. J. Jones, Springer-Verlag, New York, N.Y. (1970) p. 382.Google Scholar
  20. 20.
    Stamler, J. Brit. Heart J. 33: (Suppl.) 145 (1971).PubMedCrossRefGoogle Scholar
  21. 21.
    The Coronary Drug Project Research Group. JAMA 214: 1303 (1970).CrossRefGoogle Scholar
  22. 22.
    The Coronary Drug Project Research Group (1972) in press.Google Scholar
  23. 23.
    White, P. D. Heart Disease, 3rd Ed., Macmillan, New York, N.Y. (1944) p. 478.Google Scholar
  24. 24.
    Katz, L. N. and J. Stamler. Experimental Atherosclerosis, Charles C. Thomas, Springfield, Illinois (1953).Google Scholar
  25. 25.
    Katz, L. N., J. Stamler, and R. P. Pick. Nutrition and Atherosclerosis, Lea and Febiger, Philadelphia, Pa. (1958).Google Scholar
  26. 26.
    Wissler, R. W. Progr. Biochem. Pharmacol. 4: 378 (1968).Google Scholar
  27. 27.
    Armstrong, M. L., E. D. Warner, and W. E. Connor. Circ. Res. 27: 59 (1970).PubMedCrossRefGoogle Scholar
  28. 28.
    McGill, H. C., Jr. (Ed.) Geographic Pathology of Atherosclerosis, Williams and Wilkins, Baltimore, Md. (1968).Google Scholar
  29. 29.
    American Public Health Association Symposium. Amer. J Public Health 47: No. 4, Pt. 2 (1957).Google Scholar
  30. 30.
    Rinzler, S. H. Bull. N. Y. Acad. Med. 44: 936 (1968).PubMedGoogle Scholar
  31. 31.
    Turpeinen, O., M. Miettinen, M. J. Karvonen, P. Roine, M. Pekkarinen, E.J. Lehtosuo, and P. Alivitra. Amer. J. Clin. Nutr. 21: 255 (1968).PubMedGoogle Scholar
  32. 32.
    Dayton, S., M. L. Pearce, S. Hashimoto, W. J. Dixon, and U. Tomiyasu. Circulation 40: Suppl. 2 (1969).Google Scholar
  33. 33.
    Ederer, F., P. Leren, O. Turpeinen, and I. D. Frantz, Jr. Lancet 2: 203 (1971).CrossRefGoogle Scholar
  34. 34.
    Dayton, S., in Pharmacological Control of Lipid Metabolism, Proc. Fourth International Symp. on Drugs Affecting Lipid Metabolism. (Eds.) W. L. Holmes, R. Paoletti and D. Kritchevsky, Plenum Press, New York, N.Y. (1972) p. 245.CrossRefGoogle Scholar
  35. 35.
    Turpeinen, O., in Pharmacological Control of Lipid Metabolism, Proc. Fourth International Symp. on Drugs Affecting Lipid Metabolism. (Eds.) W. L. Holmes, R. Paoletti and D. Kritchevsky, Plenum Press, New York, N. Y. (1972) p. 207.CrossRefGoogle Scholar
  36. 36.
    Frantz, I. Personal Communication.Google Scholar
  37. 37.
    Oliver, M. Personal Communication.Google Scholar
  38. 38.
    Rose, G. Personal Communication.Google Scholar
  39. 39.
    Tibblin, G. Personal Communication.Google Scholar
  40. 40.
    Stamler, J. Progr. Cardiovasc. Dis. 3: 56 (1960).CrossRefGoogle Scholar
  41. 41.
    Stamler, J., in Modern Trends in Cardiology. (Ed.) A. M. Jones, Buttersworths, London (1969) p. 88.Google Scholar
  42. 42.
    Cuttler, S. J. and F. Ederer. J. Chronic Dis. 8: 699 (1958).CrossRefGoogle Scholar
  43. 43.
    Vital Statistics of the United States, 1967, Vol. II, Part A, Mortality, U.S. Department of Health, Education and Welfare, PHS, Washington, D. C. (1969).Google Scholar
  44. 44.
    Lew, E. A., in The Epidemiology of Hypertension. (Eds.) J. Stamler, R. Stamler and T. N. Pullman, Grune and Stratton, New York, N.Y. (1967) p. 392.Google Scholar

Copyright information

© Springer Science+Business Media New York 1972

Authors and Affiliations

  • Jeremiah Stamler
    • 1
    • 2
  • David M. Berkson
    • 1
    • 2
  1. 1.Dept. of Community Health and Preventive Medicine, and the Dept. of MedicineNorthwestern University Medical SchoolChicagoUSA
  2. 2.the Chicago Health Research Foundation; and the Heart Disease Control Program, Division of Adult Health and AgingChicago Board of HealthChicagoUSA

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