The Pharmacology of the Perinatal Period

  • George M. Maxwell


This period is divisible into two phases, the intrapartum phase which begins with the onset of labour and ends with the delivery of the child. The postpartum phase is when the infant is born, and has achieved independent existence.


Premature Infant Perinatal Period Methoxyflu Rane Hyaline Membrane Disease Respiratory Stimulant 
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Suggestions for Further Reading

  1. Aranda, J.V., Turmen, T. and Sasyniuk, B.I. (1980) ‘Pharmacokinetics of Diuretics and Methylxanthines in the Neonate’, Eur. J. Clin. Pharmacol., 18, 55 - 63CrossRefGoogle Scholar
  2. Berman, W., Dubynsky, O., Whitman, V., Friedman, Z. and Maisels, M.J. (1978) ‘Digoxin Therapy in Low Birth Weight Infants with Patent Ductus Arteriosus’, J. Pediat, 93, 652 - 655CrossRefGoogle Scholar
  3. Dutton, G.J. (1978) ‘Development Aspects of Drug Conjugation, with Special Reference to Glucuronidation’, Ann. Rev. Pharmacol. Toxicol., 18, 18 - 35CrossRefGoogle Scholar
  4. Eichenwald, H. and McCracken, G.H. (1978) ‘Antimicrobial Therapy in Infants and Children’, J. Pediat., 93, 337 - 377CrossRefGoogle Scholar
  5. Evans, M.A., Bhat, R., Vidyasaquak, D., Vadapalli, M., Fisher, E. and Hastreiter, A. (1979) ‘Gestational Age and Indomethacin Elimination in the Neonate’, Clin. Pharmacol Ther., 26, 746 - 751Google Scholar
  6. Green, T.P., O’Dean, R.F. and Mirkin, B.L. (1979) ‘Determinants of Drug Disposition and Effect in the Fetus’, Ann. Rev. Pharmacol. Toxicol., 19, 285 - 322CrossRefGoogle Scholar
  7. Heimann, G. and Gladjke, F. (1977) ‘Pharmacokinetics of Phenobarbital in Childhood’, Eur. J. Clin. Pharmacol, 12, 305 - 310CrossRefGoogle Scholar
  8. Hook, J.B. and Bailie, M.D. (1979) ‘Perinatal Renal Pharmacology’, Ann. Rev. Pharmacol. Toxicol., 19, 491 - 509CrossRefGoogle Scholar
  9. McCracken, G., Ginsberg, G., Chraive, D.F., Thomas, M.I., and Horton, I.J. (1973) ‘Clinical Pharmacology of Penicillin in Newborn Infants’, J. Pediat., 82, 692 - 698CrossRefGoogle Scholar

Copyright information

© George M. Maxwell 1984

Authors and Affiliations

  • George M. Maxwell
    • 1
  1. 1.University of AdelaideAustralia

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