The Pharmacology of the Fetus and Placenta

  • George M. Maxwell


It is convenient and necessary to consider the fetus and placenta together. The one exists for the other, each has the same origin, and to some extent shares the same pharmacological properties. This section will recall some general structural and functional properties of the feto-placental unit; then for each separately, the likely modes of drug-absorption, metabolism and disposition will be considered. The chapter will conclude with a comment on human teratology.


Fetal Tissue Fetal Alcohol Syndrome Fetal Circulation Fetal Kidney Placental Lactogen 
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  1. Boyd, J.D. and Hamilton, W.J. (1970) The Human Placenta (W. Heffer and Sons, Cambridge )Google Scholar
  2. Dawes, G.S. (1973) ‘A Theoretical Analysis of Fetal Drug Equilibrium’, in Fetal Pharmacology (ed. L.O. Boréus, Raven Press, New York ), pp. 381 - 399Google Scholar
  3. Levy, G. and Hayton, W.L. (1973) ‘Pharmacokinetic Aspects of Placental Drug Transfer’, in Fetal Pharmacology (ed. L.O. Boréus, Raven Press, New York ), pp. 29 - 39Google Scholar
  4. Rudolph, A.M., Heymann, M.A., Teramo, K.A.W., Barrett, C.T. and Ralhä, N.C.R. (1971) ‘Studies in the Circulation of the Previable Human Fetus’, Pediat. Res., 15, 452 - 465CrossRefGoogle Scholar

Copyright information

© George M. Maxwell 1984

Authors and Affiliations

  • George M. Maxwell
    • 1
  1. 1.University of AdelaideAustralia

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