Principles of Drug Action and Disposition

  • George M. Maxwell


A majority of drugs are chemicals with a variety of functional groupings such as acids, alcohols, amides, bases, esters, imides, inorganic salts, ketones, sulphones and neutral small molecules. Many active drugs are weak acids or bases, and therefore in solution can exist in the ionised or non-ionised form.


Drug Action Basic Drug Lipid Solubility Acid Drug Polycyclic Hydrocarbon 


Unable to display preview. Download preview PDF.

Unable to display preview. Download preview PDF.


  1. Bowman, W.C. and Rand, M.J. (1980) Textbook of Pharmacology, 2nd edn (Blackwell Scientific, Oxford), pp. 39.1–39.13Google Scholar
  2. LaDu, B.N., Mandel, H.G. and Way, E.L. (eds) (1971) Fundamentals of Drug Metabolism and Drug Disposition ( Williams and Wilkins, Baltimore )Google Scholar
  3. Lodish, H.F. and James, E. (1979) ‘The Assembly of Cell-membranes’, Scientific American, 240 (1), 48–63CrossRefGoogle Scholar
  4. Saunders, L. (1974) The Absorption and Distribution of Drugs ( Ballière Tindall, London )Google Scholar

Copyright information

© George M. Maxwell 1984

Authors and Affiliations

  • George M. Maxwell
    • 1
  1. 1.University of AdelaideAustralia

Personalised recommendations