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Mammalian Liver Alcohol Dehydrogenases

  • Regina Pietruszko
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 56)

Abstract

In mammals, ethanol metabolism takes place mainly in the liver where it is first converted to acetaldehyde and further to acetic acid (1,2,3). In experimental animals and in humans (4), liver alcohol dehydrogenase (ADH) is responsible for the metabolism of at least 80% of administered ethanol, at concentrations below 0.2% the contribution of any other ethanol metabolizing systems being relatively small (5).

Keywords

Human Liver Alcohol Dehydrogenase Ternary Complex Nicotinamide Adenine Dinucleotide Phosphate Steroid Activity 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1975

Authors and Affiliations

  • Regina Pietruszko
    • 1
  1. 1.Center of Alcohol StudiesRutgers UniversityNew BrunswickUSA

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