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The Role of Glycoproteins in the Life Cycle of the Cellular Slime Mold Dictyostelium discoideum

  • Ellen J. Henderson

Abstract

The cellular slime molds have been studied for a number of years as a model for analysis of developmental processes. The most commonly used species is Dictyostelium discoideum, which was first discovered in 1935 by Kenneth Raper, whose elegant pioneering studies soon attracted others to work with this organism. Raper’s 1940 report in the Journal of the Elisha Mitchell Scientific Society remains a classic. In the 1950s and 1960s, there were a handful of laboratories around the world working on D. discoideum, and they proved the usefulness of this model organism as a source of biochemical and molecular information about developmental processes, and generated an essentially exponential growth in the number of laboratories working on slime molds. The organism’s popularity was spread considerably with Bonner’s excellent monograph in 1967 and with the more recent volumes from Loomis (1975, 1982), which are the scientific equivalents of the Bible in many a laboratory. Currently, there is a vast literature on this organism; Loomis (1982) has assembled a bibliography of 1800 publications. The following description of the life cycle of D. discoideum is necessarily brief and is intended as a summary for those not acquainted with this organism. My apologies go to colleagues for the absence of individual citations of their contributions in this section. The non-Dictyosteliac can find the original citations in the volumes noted above.

Keywords

Fruiting Body Contact Site Dictyostelium Discoideum Slime Mold Cohesion Element 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1984

Authors and Affiliations

  • Ellen J. Henderson
    • 1
  1. 1.Department of BiologyGeorgetown UniversityUSA

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