Abstract
The final proof of the activation of the kininsystem is the demonstration of the liberation of free kinin into the blood or other biological fluids. The current methods for free kinin determination include rapid denaturation of the blood proteins (including kallikreins, kininogens and kininases), purification of the extracts to eliminate active substances interfering with the assay, concentration of the extracts, and finally the assay for which smooth muscle has mostly been used.
Access this chapter
Tax calculation will be finalised at checkout
Purchases are for personal use only
Preview
Unable to display preview. Download preview PDF.
References
Abe,K., Watanabe,N., Kumagai,N., Mouri,T., Seki,T. and Yoshinaga,K.; Tohoku J.exp.Med. 82, 103, 1966.
Allwood,M.J. and Lewis,G.P.; J.Physiol.(Lond.) 170, 571, 1964.
Binia,A., Fasciolo,J.C. and Carretero,O.A.; Acta physiol. latino-amer. 12, 101, 1963.
Brocklehurst,W.E. and Zeitlin,I.J.; J.Physiol. (Lond.) 121, 417, 1967.
Edery,H.; Brit.J.Pharmacol. 22, 371, 1964.
Louhija,A. and Sipilä,R.; Biochem.Pharmacol. In press.
Melmon,K.L., Cline,M.J., Hughes,T. and Nies,A.S.; J.clin.Invest. 42, 1295, 1968.
Oates,J.A., Melmon,K., Sjoerdsma,A., Gillespie,L. and Mason,D.T.; Lancet I, 514, 1964.
Webster,M.E. and Gilmore,J.P.; Biochem.Pharmacol. 14, 1161, 1965.
Zacest,R. and Mashford,M.L.; Aust.J.exp.Biol.med. Sci. 45, 89, 1967.
Author information
Authors and Affiliations
Editor information
Editors and Affiliations
Rights and permissions
Copyright information
© 1972 Plenum Press, New York
About this chapter
Cite this chapter
Louhija, A., Sipilä, R. (1972). The Presence of a Smooth Muscle Contracting and Bradykinin Potentiating Factor in Plasma. In: Back, N., Sicuteri, F. (eds) Vasopeptides. Advances in Experimental Medicine and Biology, vol 21. Springer, Boston, MA. https://doi.org/10.1007/978-1-4684-7439-8_11
Download citation
DOI: https://doi.org/10.1007/978-1-4684-7439-8_11
Publisher Name: Springer, Boston, MA
Print ISBN: 978-1-4684-7441-1
Online ISBN: 978-1-4684-7439-8
eBook Packages: Springer Book Archive