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Surfactant in Pulmonary Oxygen Toxicity

  • S. Armbruster
  • J. Klein
  • E. M. Stouten
  • W. Erdmann
  • B. Lachmann
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 215)

Abstract

Prolonged continuous exposure to high concentrations of oxygen can be lethal, due to respiratory failure. However, the cause of this respiratory failure is not known. The present study was designed to investigate the role of pulmonary surfactant in the development of respiratory failure induced by high concentrations of oxygen.

Keywords

Respiratory Failure Surface Tension Measurement Pulmonary Surfactant Lung Lavage Insufflation Pressure 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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References

  1. Lachmann, B., Robertson, B. and Vogel, J. (1980). In vivo lung lavage as an experimental model of the respiratory distress syndrome. Acta Anaesth. Scand. 24, 231.CrossRefGoogle Scholar
  2. Smith, R.M., Rogers, R.M., Horton, F.O. and McCallum, R.E. (1981). Lung mechanics and a simultaneous comparison of alveolar pleural and peritoneal phagocytic cells lavaged from fasted infection-free oxygen toxic rats. Chest, 80, (July Suppl) 15–185.CrossRefGoogle Scholar

Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • S. Armbruster
    • 1
  • J. Klein
    • 1
  • E. M. Stouten
    • 1
  • W. Erdmann
    • 1
  • B. Lachmann
    • 1
  1. 1.Department of AnaesthesiaErasmus University RotterdamThe Netherlands

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