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Highly Polymerized Human Haemoglobin as an Oxygen-Carrying Blood Substitute

  • W. K. R. Barnikol
  • O. Burkhard
Part of the Advances in Experimental Medicine and Biology book series (AEMB, volume 215)

Abstract

There are many situations where a quick substitution of erythrocytes is warranted. However the need for blood typing generally causes considerable delay in getting the matched erythrocytes. Furthermore, in the case of a catastrophe or war there may be a great demand for blood which cannot be delivered by the blood donors available. In these cases an artificial oxygen-carrying blood substitute which does not require blood typing and which can be stored for a considerable time may save lives. For example, in the case of an accident such a blood substitute is available at once. Another field of application for such solutions lies in chronic peripheral arterial occlusion. It has been shown that in these cases an oxygen-carrying blood substitute is superior to simple isoncotic volume substitution (Moss et al., 1953).

Keywords

Blue Dextran Blood Substitute Hemoglobin Solution Measure Residence Time Perfluorochemical Emulsion 
These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.

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Copyright information

© Plenum Press, New York 1987

Authors and Affiliations

  • W. K. R. Barnikol
    • 1
  • O. Burkhard
    • 2
  1. 1.Physiologisches InstitutJohannes Gutenberg-UniversitaetMainzGermany
  2. 2.Haematologische AbteilungJohannes Gutenberg-UniversitaetMainzGermany

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