Cerebral Cortical Oxygenation and Perfusion during Progressive Normovolaemic Haemodilution with Hetastarch (Volex) and Fluosol-DA
In a previous study on the effects of normovolaemic haemodilution with Hetastarch on cerebral cortical oxygenation and perfusion, we found that cortical tissue PO2 (PtO2) was unchanged between haematocrits (Hct) of 45 to 38%, but then fell at a rate of about 2.4% per 1% decrease in Hct between Hct of 38% to 5% (Shinozuka, Nemoto and Bleyaert, 1984). Fluosol-DA may delay the fall in cerebral cortical PtO2 during normovolaemic haemodilution compared with haemodilution with Hetastarch.
KeywordsCerebral Vasospasm Pancuronium Bromide Group Anesthesia Local Cerebral Blood Flow Platinum Microelectrode
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