Lipid Peroxidation by Phagocytes

  • Bernard M. Babior
Part of the NATO ASI Series book series (NSSA, volume 189)

Abstract

Professional phagocytes (neutrophils, eosinophils, mononuclear phagocytes) are uniquely endowed with the capacity to manufacture large quantities of highly reactive oxidizing agents for use in the destruction of invading pathogens, both unicellular and multicellular. This capacity arises because of the presence in these cells of an enzyme known as the respiratory burst oxidase that catalyzes the one-electron reduction of oxygen to 02 at the expense of NADPH

Keywords

Respiration Prostaglandin NADPH Catalase Ferritin 

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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Bernard M. Babior
    • 1
  1. 1.Department of Molecular and Experimental MedicineResearch Institute of Scripps ClinicLa JollaUSA

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