Laser Doppler Flow Measurement for the Evaluation of Cerebral Microcirculation
The intraoperative assessment of cerebral blood flow (CBF) variations would be of the utmost value to the neurosurgeon. Intraoperative monitor ing of CBF is directed to identify either the impairment of hemodynamic regulating mechanisms (autoregulation, vasoreactivity) produced by a lesion [SAH (sub aracnoidal hemorrhagy), tumor, trauma] or the modifications of local perfusion produced by surgical maneuvers. The ideal intraoperative device would not be invasive and cumbersome; moreover, it would not alter regional CBF during the detection procedures, allowing real time continuous monitoring of CBF; and the operation would not be prolonged by the flow measurement. The laser Doppler (LD) flowmeter has been extensively used to study microcirculation in various tissues.
KeywordsCerebral Blood Flow Regional Cerebral Blood Flow Surgical Maneuver Laser Doppler Flowmeter Local Perfusion
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