Mechanism of Steroid Hormone Action

  • Anders Berkenstam
  • Jan-Ake Gustafsson
Part of the NATO ASI Series Advanced Science Institutes Series book series (NSSA, volume 202)


In general, specific genes are expressed in a temporal or tissuespecific manner or are regulated in response to extracellular signals (Mitchell and Tjian, 1989). Steroid hormones constitute one such group of extracellular signals that regulate the expression of certain genes by interacting with intracellular receptor proteins. These receptors belong to a family of ligand-activated enhancer-binding proteins i.e. the steroid/thyroid hormone receptor super-family, that also includes receptors for retinoic acid, thyroid hormone and some yet unidentified ligands (Evans, 1988).


Glucocorticoid Receptor Steroid Hormone Receptor Mineralocorticoid Receptor Mouse Mammary Tumor Virus Human Oestrogen Receptor 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Anders Berkenstam
    • 1
  • Jan-Ake Gustafsson
    • 1
  1. 1.Department of Medical Nutrition Karolinska InstituteHuddinge University Hospital F60 NovumHuddingeSweden

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