Posttranslational Modification by Phosphorylation: Control of Cytochrome P450 and Associated Enzymes

  • Walter Pyerin
  • Hisaaki Taniguchi
Part of the NATO ASI Series Advanced Science Institutes Series book series (NSSA, volume 202)


Regulation of proteins by posttranslational modification is of crucial importance for eucaryotic cells in particular because of the relatively long half-lives of their mRNAs and the resulting lack of rapid protein regulation at the nucleic acid level. The phosphorylation of proteins (and their dephosphorylation) has emerged as the most widespread and important posttranslational regulatory device. It is now known to occur in all types of cells and in virtually all cellular compartments and organelles (1.2).


Microsomal Protein Phosphoryl Group P450 Reductase Phosphorylation Degree Casein Kinase Type 
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Copyright information

© Plenum Press, New York 1991

Authors and Affiliations

  • Walter Pyerin
    • 1
  • Hisaaki Taniguchi
    • 1
  1. 1.Institute of Experimental PathologyGerman Cancer Research CenterHeidelbergFederal Republic of Germany

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