In Vivo Correlates of In Vitro Studies of Axonal Guidance: Retinal Transplantation in the Mammalian Retinotectal System

  • Mark Hankin
  • Raymond Lund
Part of the NATO ASI Series book series (NSSA, volume 192)


It is nearly 100 years since Ramón y Cajal first described the bulbous ends of immature axons (see Ramón y Cajal, 1937), and 80 years since Harrison (1910) provided convincing evidence that these structures were, indeed, growth cones. In the intervening time, a great deal of interest has been directed towards elucidating the mechanisms by which axons are first guided along their pathway of outgrowth to their target regions, and then are matched with appropriate sets of neurons to form functional synaptic circuits.


Growth Cone Retinal Ganglion Cell Superior Colliculus Optic Tectum Glia Limitans 
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Copyright information

© Plenum Press, New York 1990

Authors and Affiliations

  • Mark Hankin
    • 1
  • Raymond Lund
    • 1
  1. 1.Department of Neurobiology Anatomy and Cell ScienceUniversity of PittsburghPittsburghUSA

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