Antiviral Chemotherapy: An Introduction and Reasons for the Slow Progress, Particularly towards Rational Design
Six years ago, Sir Charles Stuart-Harris opened a Beecham Colloquium on Problems of Antiviral Therapy1 with a lecture entitled “Antiviral Chemotherapy: an Introduction and Apology for the Slow Progress”. Today, I think we no longer have to apologise; progress is still very slow but as I hope to show, there are many reasons for this, some of which are outside the control of scientists and given the constraints, no one can reasonably expect progress to be any faster.
KeywordsHerpes Simplex Virus Type Thymidine Kinase Nucleoside Analogue Viral Polymerase Naive Assumption
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