The Use of Wheat Bran to Decrease Calcium Excretion and to Treat Calcium Oxalate Stone Disease
There are conflicting reports on the effect of long-term administration of wheat bran on plasma calcium and the urinary excretion of calcium. Heaton and Pomare1 gave their patients 38 g of bran daily for 4 to 9 weeks and found a significant decrease in plasma calcium. In contrast, Brodribb and Humphreys2 administered 24 g of wheat bran daily for 6 months and described a significant decrease in calcium excretion without a change in plasma calcium. Other authors3 have found that bulk material is able to bind calcium. In one-third of the patients with calcium oxalate stones idiopathic hypercalciuria is present and is usually treated by reduction of milk and milk products or by administration of thiazides. Based on these and other observations4,5 we have used wheat bran to decrease the urinary excretion of calcium as a treatment for calcium oxalate stones.
KeywordsUric Acid Urinary Excretion Oxalic Acid Wheat Bran Calcium Oxalate
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- 5.P. J. R. Shaf, G. Williams, and N. A. Green, in: “Urolithiasis, Clinical and Basic Research”, L. H. Smith, W. G. Robertson, and B. Finlayson, eds., Plenum, New York (1981).Google Scholar