Urinary and Serum Sulfate in Idiopathic Recurrent Calcium Urolithiasis (RCU)
Sulfate is present in considerable amounts in human urine and serum, but little is known about sulfate in RCU. There are two reasons for a possible relationship between sulfate and stone-formation: (i) sulfate ions in tubular fluid or urine compete with oxalate for complexing with calcium ions, and (ii) inorganic sulfate under certain dietary conditions correlates directly with urinary calcium, suggesting that idiopathic hypercalciuria (I-HC) may be linked with either a high protein level in the diet, enhanced intestinal absorption of dietary sulfate, increased hepatic sulfur oxidation or altered renal sulfate handling. We report on the sulfate in the 24-h and 2-h fasting urines, and in the serum of RCU subjects and controls.
KeywordsInorganic Sulfate Stone Patient Idiopathic Hypercalciuria Tubular Fluid Excretion Relate
Unable to display preview. Download preview PDF.
- 1.N. Weissman, and V. J. Pileggi, in: “Clinical Chemistry, Principles and Technics”, R. J. Henry, D. C. Camion, J. W. Winkelman, eds., Harper & Row, Hagerstown, New York (1974).Google Scholar
- 2.S. A. Schuette, M. Hegsted, M. B. Zemel, and M. H. Linkswiler, J. Nutr. 111:210 (1981).Google Scholar
- 4.G. Ploss, P. O. Schwulle, and A. Siegel, in: “Urolithiasis and Related Clinical Research”, P. O. Schwille, L. H. Smith, W. G. Robertson, W. Vahlensieck, eds., Plenum, New York (1985).Google Scholar