Urinary and Serum Sulfate in Idiopathic Recurrent Calcium Urolithiasis (RCU)

  • P. O. Schwille
  • A. Hamper
  • A. Sigel


Sulfate is present in considerable amounts in human urine and serum, but little is known about sulfate in RCU. There are two reasons for a possible relationship between sulfate and stone-formation: (i) sulfate ions in tubular fluid or urine compete with oxalate for complexing with calcium ions, and (ii) inorganic sulfate under certain dietary conditions correlates directly with urinary calcium, suggesting that idiopathic hypercalciuria (I-HC) may be linked with either a high protein level in the diet, enhanced intestinal absorption of dietary sulfate, increased hepatic sulfur oxidation or altered renal sulfate handling. We report on the sulfate in the 24-h and 2-h fasting urines, and in the serum of RCU subjects and controls.


Inorganic Sulfate Stone Patient Idiopathic Hypercalciuria Tubular Fluid Excretion Relate 
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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • P. O. Schwille
    • 1
  • A. Hamper
    • 1
  • A. Sigel
    • 1
  1. 1.Mineral Metabolism and Endocrine Research Laboratory and Depts. of Surgery and UrologyUniversity of ErlangenGermany

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