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The Influence of Glucose and Insulin on Calcium Excretion in the Urine

  • R. G. Willis
  • R. Green
  • C. Gordon
  • N. J. Blacklock

Abstract

Administration of refined carbohydrate or glucose to man increases calcium (Ca) excretion in the urine1, but it is not known whether or not this is a direct effect. The normal increase in Ca excretion which occurs following the administration of glucose is exaggerated in stone forming patients2,3, and such patients frequently show an abnormal plasma insulin response to a standard glucose tolerance test4. This paper investigates in the rat the causes of the increased Ca excretion provoked by glucose and the suggestion that hyperinsulinaemia per se may produce a similar increase in Ca excretion5.

Keywords

Glomerular Filtration Rate Plasma Insulin Insulin Infusion Plasma Glucose Concentration Glucose Infusion 
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References

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Copyright information

© Plenum Press, New York 1985

Authors and Affiliations

  • R. G. Willis
    • 1
  • R. Green
    • 1
  • C. Gordon
    • 1
  • N. J. Blacklock
    • 1
  1. 1.University Depts. of Physiology, Urology and Medicine University of ManchesterUK

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